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The Fastest
The Smallest
The Safest
Blow Fill Seal machine

A NEW and revolutionary Blow Fill Seal machine to combine container formation, aseptic filling and sealing into one continuous operation.

The Fastest
The Smallest
The Safest
Blow Fill Seal machine

A NEW and revolutionary Blow Fill Seal machine to combine container formation, aseptic fillingand sealing into one continuous operation.

Closed Parison
Technology

Meeting and Exceeding EU GMP Annex 1 requirements.
Blow Fill Seal is acknowledged as an Advanced Aseptic Technology by all International Regulators. The containers are formed and filled under Grade A conditions in a closed system, always protected from the external environment, ensuring unparalleled safety.

Productivity

SYFPAC® DUO is available in 4 different configurations:

  • micro: 4.000 units/h –27 million doses/year
  • Mini: 10.000 units/h – 66 million doses/year 
  • MAX: 20.000 units/h – 132 million doses/year
  • Hyper: 40.000 units/h – 264 million doses/year

Highest productivity/m2 ratio in the industry
Fastest machine in the market

Footprint

  • Tiny machine footprint: 6 m2 of Class C Room
  • Machine size: 1,5 m x 4,5 m – only 2,6 m high
  • Several layouts possible: single-room or on-board or stand-alone solution cabinet in a Black & White configuration

Footprint

  • Tiny machine footprint. 6 m2 of Class C Room.
  • Machine size: 1.5 m X 4 m – only 2.6 m high
  • Several layouts possible, like for example single-room or on-board or stand-alone solution cabinet in a Black & White configuration

Flexibility

  • Fill volume ranging from 0,2 ml up to 50 ml
  • SYFPAC® DUO is upgradable from Lab Scale to High-Speed production. Productivity can be increased by up to 10x at any point in time, using the SAME machine
  • Processing of PE and PP without any hardware changes, only recipe change in the HMI, as proven in decades of experience
  • Mould changeover time is now less than 10 minutes

Efficiency/Sustainability

  • Close-To-Zero Waste. Lowest plastic consumption in the industry. The amount of plastic scrap is now less than 6%
  • Savings up to 900k EUR per year in plastic consumption only
  • Up to 2,5x more production in 1/3 of the space
  • Fully electric machine: all movements are driven by servo motors

Insertion Technology

  • Insertion Technology available for the first time in a Closed Parison machine
  • Enabling new, effective and extremely cost-effective drug delivery devices such as Pre-filled Syringes, Multi-Dose Eye Drops and much more to come

Hygienic design

  • Ground-breaking process monitoring system now also available in a Closed Parison Machine. For the first time, monitoring of both Total Particles and Viables. Meeting and exceeding EU GMP Annex 1 requirements
  • Clean design to meet Pharma demands, with isolated clean area
  • Containment ready for highly potent or toxic products

Cold production

  • Coolest Blow Fill Seal Machine ever made
  • Enabling production of Temperature Sensitive products, such as Biologicals including Vaccines in a Closed Parison machine, now with unrivaled low product temperature
  • Temperature of the filled product well below 25°C

Applications

Vaccines, injectables, eye drops, biologicals, inhalations, small volume parenterals, highly potent formulation including BSL level 4 products, highly toxic products