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The Fastest
The Smallest
The Safest
Blow Fill Seal machine.

A NEW and revolutionary Blow Fill Seal machine to combine container formation, aseptic fillingand sealing into one continuous operation.

The Fastest
The Smallest
The Safest
Blow Fill Seal machine.

A NEW and revolutionary Blow Fill Seal machine to combine container formation, aseptic fillingand sealing into one continuous operation.

Closed Parison
Technology

Meeting and Exceeding EU GMP Annex 1 requirements.
Blow Fill Seal is acknowledged as an Advanced Aseptic Technology by all International Regulators. The containers are formed and filled under Grade A conditions in a closed system, always protected from the external environment, ensuring unparalleled safety.

Productivity

Productivity

SYFPAC® DUO is available in 4 different configurations:

  • micro: 4.000 units/h–27 million doses /year
  • Mini: 10.000 units/h – 66 million doses /year 
  • MAX: 20.000 units/h – 132 million doses /year
  • Hyper: 40.000 units/h – 264 million doses /year

Highest productivity/m2 ratio in the industry.
Fastest machine in the market.

  • Tiny machine footprint. 6 m2 of Class C Room.
  • Machine size: 1.5 m X 4 m – only 2.6 m high
  • Several layouts possible, like for example single-room or on-board or stand-alone solution cabinet in a Black & White configuration
  • Tiny machine footprint. 6 m2 of Class C Room.
  • Machine size: 1.5 m X 4 m – only 2.6 m high
  • Several layouts possible, like for example single-room or on-board or stand-alone solution cabinet in a Black & White configuration

Other features

Flexibility

  • SYFPAC® DUO is upgradable from Lab Scale to High-Speed production. Productivity can be increased by up to 8x at any point in time, using the SAME machine.
  • Fill volume ranging from 0.2 ml up to 50 ml
  • Processing of PE and PP without any hardware changes, only recipe change in the HMI, as proven in decades of experience.
  • Mould changeover time is now less than 10 minutes.

Efficiency/Sustainability

  • Close-To-Zero Waste. Lowest plastic consumption in the industry. The amount of plastic scrap is now less than 6%.
  • Up to 2.5x more production in 1/3 of the space
  • Savings up to 900k EUR per year in plastic consumption only!
  • SYFPAC® DUO is Fully Electric, no hydraulic oil is needed.

Hygienic design

  • Fully electric machine, all movements are driven by servo motors.
  • Clean design to meet Pharma demands, with isolated clean area.
  • Ground-breakingprocess monitoring system now also available in a Closed Parison Machine. For the first time, monitoring of both Total Particles and Viables.
  • Containment ready for highly potent or toxic products
  • Meeting and Exceeding EU GMP Annex 1 requirements
  • Proven Extrusion Technology with the longest Plastic Residence Time in the industry

Insertion Technology

  • Insertion Technology available for the first time in a Closed Parison machine.
  • Enabling new, effective and extremely cost-effective drug delivery devices such as Pre-filled Syringes, Multi-Dose Eye Drops and much more to come.

Cold production

  • Coolest Blow Fill Seal Machine ever made
  • Enabling production of Temperature Sensitive products, such as Biologicals including Vaccines in a Closed Parison machine, now with unrivaled low product temperature.
  • Temperature of the filled product well below 25°C

Applications

  • Vaccines, injectables, eye drops, biologicals, inhalations, small volume parenterals, highly potent formulation including BSL level 4 products, highly toxic products

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Contact us

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